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The First Example of Ring-Closing Olefin Metathesis of Dehydroamino Acids: An Application to the Synthesis of Azabicyclo[X.Y.0]alkanes.

โœ Scribed by Leonardo Manzoni; Matteo Colombo; Carlo Scolastico


Publisher
John Wiley and Sons
Year
2004
Weight
96 KB
Volume
35
Category
Article
ISSN
0931-7597

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โœ Francis Gosselin; William D. Lubell ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 36 KB ๐Ÿ‘ 1 views

An Olefination Entry for the Synthesis of Enantiopure ฮฑ,ฯ‰-Diaminodicarboxylates and Azabicyclo[X.Y.0]alkane Amino Acids. -Treatment of aminodicarboxylates of type (I) with methyl phosphonate and subsequent Horner-Wadsworth-Emmons olefination with aldehyde (IV) offers a new and efficient route to dia