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The First Enantioselective Syntheses of Axially Chiral Enantiomerically Pure Calix[4]resorcinarene Derivatives

✍ Scribed by Page, Philip C. Bulman; Heaney, Harry; Sampler, Edward P.


Book ID
111682085
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
95 KB
Volume
121
Category
Article
ISSN
0002-7863

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First Synthesis of Enantiomerically Pure
✍ Hormuth, Stephan ;Schade, Wolfgang ;Reißig, Hans-Ulrich πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 594 KB

## Abstract Repetitive additions to chiral 3(2__H__)‐Dihydrofuranones opened a route to the first enantiomerically pure primary helical spirocyclic compounds. Thus, addition of lithiated methoxyallene 2 to furanone 9 provided adduct 10 with excellent diastereoselectivity. Cyclization with potassium