The first diastereoselective addition of an organolithium compound to α-halocarboxylic acid esters
✍ Scribed by José Barluenga; Bruno Pedregal; José M. Concellón
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- French
- Weight
- 162 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
MgBr mediated addition of to A'and Methyl &-methylthio propionate silylketene acetal o(,p-alkoxy aldehydes is highly 3,4 syn-selective (18:l). syn-d-methylene$-hydroxy-s-alkoxy esters (6) and (8) are synthesized. We recently reported that I butyIP-dimethylamino propionate, a synthetic equivalent of
The addition of organolithium reagents to the C=-N bond of several cnflhrulosc-dcflved chiral (E)and (Z)-ketoximc ethers has been shown to be highly diastereoselectivc for the (E)-isomers. A chelated transilion state has been p~sed to explain this n~ult The addition products were converted into the
## Abstract For Abstract see ChemInform Abstract in Full Text.