✦ LIBER ✦

The first decade of molecular genetics in neurology: Changing clinical thought and practice

✍ Scribed by Dr. Lewis P. Rowland

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 864 KB
Volume: 32
Category: Article
ISSN: 0364-5134
DOI: 10.1002/ana.410320213

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Molecular genetics has had a powerful impact on clinical neurology. Definitions of disease are changing from clinical criteria to DNA analysis, resolving questions about the nature of clinically similar but not identical diseases. Genetic counseling is more reliable. Concepts of mendelian inheritance are being tested and new forms of mutation have been discovered to explain anticipation. Nonmendelian forms of inheritance have emerged; concepts of pathogenesis are on a more secure footing; and novel treatments are being explored.

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