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The First Asymmetric Addition of Organogallium to Aldehydes Catalyzed by Chiral Titanium Catalysts.

✍ Scribed by Zhenya Dai; Chengjian Zhu; Minghua Yang; Yunfa Zheng; Yi Pan


Publisher
John Wiley and Sons
Year
2005
Weight
28 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract A series of β‐sulfonamide alcohol ligands were synthesized from L‐phenylalanine. Titanium complexes of these compounds were used to catalyze the asymmetric addition of phenylacetylene to a number of aldehydes. When the conditions were optimized, 20β€…molβ€…% of ligand **8a** catalyzed the r