## Abstract Sphingolipids play a relevant role in cellβcell interaction, communication, and migration. We studied the sphingolipid content in the murine hepatic stellate cell line GRX, which expresses the myofibroblast phenotype, and can be induced in vitro to display the fatβstoring phenotype. Lip
β¦ LIBER β¦
The Fibronectin-Derived Antiadhesive Peptides Suppress the Myofibroblastic Conversion of Rat Hepatic Stellate Cells
β Scribed by Rina Kato; Sadahiro Kamiya; Masaaki Ueki; Hirofumi Yajima; Tadahiro Ishii; Hiroshi Nakamura; Takashi Katayama; Fumio Fukai
- Book ID
- 115603966
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 435 KB
- Volume
- 265
- Category
- Article
- ISSN
- 0014-4827
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Platelet-derived growth factor (PDGF) is the most potent mitogen for hepatic stellate cells (HSCs) in vitro. The aim of this study was to investigate the role of the lipid-derived second messenger phosphatidic acid (PA) in mediating this effect and, in particular, to determine its interaction with t