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The fibronectin attachment protein of bacillus Calmette-Guerin (BCG) mediates antitumor activity

✍ Scribed by Haley W. Sinn; Bennett D. Elzey; Robert J. Jensen; Xiuqin Zhao; Weicheng Zhao; Timothy L. Ratliff


Book ID
105967318
Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
464 KB
Volume
57
Category
Article
ISSN
0340-7004

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Intravesical Mycobacterium bovis bacillus Calmette-Gu\*erin (BCG) is the treatment of choice for superficial bladder cancer. Previous studies showed that attachment of BCG to fibronectin within the bladder was necessary for mediation of the antitumor response. Further studies identified a bacterial