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The feasibility of establishing a programme of adjuvant autologous vaccination for renal cell carcinoma

✍ Scribed by Robin J. Prestwich; Karen J. Scott; Joanne Brown; Patricia Harnden; Peter Whelan; Jon Cartledge; Dearbhaile O’Donnell; Hardev S. Pandha; Peter J. Selby; Rosamund E. Banks; Alison E. Merrick; Alan A. Melcher

Book ID: 109054433
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 207 KB
Volume: 103
Category: Article
ISSN: 1464-4096
DOI: 10.1111/j.1464-410x.2008.08113.x

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Vaccination with tumour cells genetically modified to support induction of an immune response either by production of cytokines or expression of co-stimulatory molecules provides a promising therapeutic approach. We have evaluated the efficiency of tumour vaccination using RENCA cells, a renal cell