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The farnesyl transferase inhibitor, FTI-277, inhibits growth and induces apoptosis in drug-resistant myeloma tumor cells

โœ Scribed by Bolick, S C E; Landowski, T H; Boulware, D; Oshiro, M M; Ohkanda, J; Hamilton, A D; Sebti, S M; Dalton, W S

Book ID
110055386
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
403 KB
Volume
17
Category
Article
ISSN
0887-6924

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## Abstract Multimodal therapies play important roles in the treatment of osteosarcoma (OS) and Ewing's family of tumors (EFTs), two most frequent malignant bone tumors. Although the clinical outcome of primary OS and EFTs is greatly improved, the relapsed cases often are associated with multidrug