The Eye: Basic Sciences in Practice

✍ Scribed by John V. Forrester, Andrew D. Dick, Paul G. McMenamin, Fiona Roberts, Eric Pearlman

• Publisher: Elsevier
• Year: 2021
• Tongue: English
• Leaves: 667
• Edition: 5
• Category: Library

✦ Synopsis

The Eye: Basic Sciences in Practice provides highly accessible, one-stop coverage of all the essential basic science required by today’s ophthalmologists and optometrists in training. It is also core reading for those embarking on a career in visual and ophthalmic science, as well as an invaluable, current refresher for the range of practitioners working in this area.

Building on previous success, this fifth edition has been fully revised in line with current curricula, key research developments and clinical best practice. It succinctly incorporates critical developments in fast-moving fields related to the eye and vision, including genetics, pharmacology, microbiology, immunology, pathology, neurophysiology, neuroanatomy and imaging. Topical coverage includes:

Major advances in the search for new genes underpinning disease in ophthalmology
The emergence of new infections such as Ebola, Zika and COVID-19
The importance of the gastrointestinal tract as an immune organ and its functional dependence on the microbiome
Key aspects of melanopsin, melatonin and new ways of light sensing
Also, (print purchasers) benefit from access to the complete, fully searchable electronic text, with integrated video and other bonus materials to further explain and expand on key concepts. This combines to make The Eye a more flexible, comprehensive and engaging learning package than ever before.

The only all-embracing textbook of the basic sciences suitable for trainee ophthalmologists, optometrists and vision scientists.
Utilising an attractive page design with over 300 colour drawings and 200 photographs this is an attractive and accessible text to learn from.
The text presents in a readable form an account of all the basic sciences necessary for an understanding of the eye – anatomy, embryology, genetics, biochemistry, physiology, pharmacology, immunology, microbiology and infection and pathology.

✦ Table of Contents

Cover
The Eye Basic Sciences in Practice
Copyright
Contents
Preface
Acknowledgements
1- Anatomy of the eye and orbit
Osteology of the skull and orbits
Structure of the eye
Orbital contents
Ocular appendages (adnexa)
Anatomy of the visual pathway
2 - Embryology and early development of the eye and adnexa
General embryology
Ocular embryology: general introduction
Optic nerve and disc development
Development of the fibrous coat of the eye
Development of the uveal tract
Development of extraocular muscles
3 - Genetics
Chromosomes and cell division
Molecular genetics (DNA and genes)
Chromosome defects and gene mutations
Clinical genetics
Population genetics
Understanding the human genome: DNA analysis
Molecular and cell biology: controlling cell destiny
Molecular genetics and ophthalmology
4 - Biochemistry and cell biology
The ‘omics’ creed
Cells and tissues
Biochemical pathways that affect ocular function
The ocular surface
Cornea and sclera
The uveal tract
Aqueous humour dynamics
The lens
The vitreous body
The retina
The chemistry of the visual response
5 - Physiology of vision and the visual system
Introduction
Light detection and dark adaptation
Visual acuity and contrast sensitivity
Electrophysiology of the visual system
Colour vision
Visual perception
Physiology of ocular movement
6 - General and ocular pharmacology
Introduction
Pharmacodynamics: drug handling by the body
Drug–receptor interactions
Ocular pharmacology: drug handling by cells and tissues of the eye
Reconstituting the tear film
Ocular drugs and the autonomic nervous system
A drug-free approach to treating glaucoma
Eicosanoids affect multiple ocular functions
Serotonin: a potent neurotransmitter
Glucocorticoids
Ocular toxicity from systemic administration of drugs
7 - Immunology
Introduction
Overview of the immune system
INNATE IMMUNITY, PAMPS AND DAMPS
THE HYGIENE HYPOTHESIS
Cells and molecules of the immune system
IMMUNE PRIVILEGE IN THE CENTRAL NERVOUS SYSTEM (CNS)
Conclusion
References
Further reading
8 - Microbial infections of the eye
Introduction
Host defences at the ocular surface
Viral infections of the eye
Bacterial infections of the eye
Fungal infections of the eye
9 - Pathology
Cell and tissue damage
Healing and repair
Inflammation
Metabolic disease
Ageing, degeneration and dystrophies
Neoplasia
Addendum

✦ Subjects

Ophthalmology; Eye Anatomy & Physiology; Optometry