The extracellular space and matrix of gliomas
โ Scribed by Josef Zamecnik
- Publisher
- Springer-Verlag
- Year
- 2005
- Tongue
- English
- Weight
- 514 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0001-6322
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๐ SIMILAR VOLUMES
Tumor cell migration through the extracellular space (ECS) might be affected by its pore size and extracellular matrix molecule content. ECS volume fraction alpha (alpha = ECS volume/total tissue volume), tortuosity lambda (lambda(2) = free/apparent diffusion coefficient) and nonspecific uptake k' w
A novel human glioma-associated extracellular matrix (ECM) glycoprotein has been identified by murine monoclonal antibody 81C6. The glycoprotein, designated GMEM, is expressed in the ECM of glioma and mesenchymal cell cultures, in the perivascular matrix of endothelial proliferations of human glioma
## Abstract We have investigated the expression of integrins in C6 glioma, a chemicallyโinduced glial tumor cell line from rat brain. Immunochemical analysis revealed that C6 cells express sets of integrin receptor complexes which immunologically and electrophoretically are indistinguishable from t
## Malignant gliomas are characterized by an extensive invasion of tumor cells into the normal brain parenchyma. A substantial amount of data indicates that cell movement in general is regulated by specific interactions between extracellular matrix components and specific cell-surface receptors. I