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The extent of phase I and phase II reactions is affected by the choice of enzyme used to prepare rat hepatocytes

✍ Scribed by J.A. Sinclair; C. Henderson; I. Martin; M.H. Grant; J.N.A. Tettey


Book ID
113517882
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
489 KB
Volume
179
Category
Article
ISSN
0009-2797

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The role of diacylglycerol (DAG) in hormonal induction of S phase was investigated in primary cultures of rat hepatocytes. In this model, several agonists that bind to G protein-coupled receptors act as comitogens when added to the cells soon after plating (i.e., in Go/early Gl phase), while the cel