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The extent of genetic variation in the CCR5 gene

✍ Scribed by Ansari-Lari, M. Ali; Liu, Xiao-Mei; Metzker, Michael L.; Rut, Andrew R.; Gibbs, Richard A.


Book ID
109916518
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
439 KB
Volume
16
Category
Article
ISSN
1061-4036

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## Abstract Homozygous (Ξ”ccr5/Ξ”ccr5) and heterozygous (CCR5/Ξ”ccr5) deletions in the β‐chemokine receptor 5 (CCR5) gene, which encodes for the major co‐receptor for macrophage‐tropic HIV‐1 entry, have been implicated in resistance to HIV infection and in protection against disease progression, respe