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The expressions of Bcl-2 and Bax in gastric carcinoma and precancerous lesions

✍ Scribed by Yi Xinhao; Wu Qisong; Li Huahui; Wu Jianmin


Publisher
Springer
Year
2008
Tongue
English
Weight
249 KB
Volume
7
Category
Article
ISSN
1610-1979

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Bcl-2 is a proto-oncogene which is involved in prolonging cell survival by inhibiting programmed cell death. Bax and bcl-x are members of the bcl-2 family; when overexpressed, they can counteract the ability of bcl-2 to inhibit apoptosis. This suggests a model in which the ratios of bcl-2 to bax and