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The Expression, Refolding, and Purification of the Catalytic Domain of Human Collagenase-3 (MMP-13)

✍ Scribed by Naveen Pathak; Shou-Ih Hu; James A. Koehn


Book ID
115645394
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
251 KB
Volume
14
Category
Article
ISSN
1046-5928

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## Abstract Collagenase‐3 (MMP‐13) is characterized by an exceptionally wide substrate specificity and restricted expression. MMP‐13 is 1 of the few MMPs primarily expressed by tumor cells in malignant tumors, __e.g.__, squamous cell carcinomas and its expression correlates with their invasion capa