The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome in ‘pure’ ductal carcinoma in situ of the breast
✍ Scribed by M A J De Roos; B Van Der Vegt; J L Peterse; C Patriarca; J De Vries; G H De Bock; J Wesseling
- Book ID
- 108780371
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 726 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0309-0167
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MUC1 mucin is a high molecular weight transmembrane glycoprotein expressed on the apical cell surface of normal glandular epithelia. In many human adenocarcinomas, this protein is up-regulated and/or underglycosylated, and its expression changes from apical to the entire cell membrane. It is thought
## Background: Mammography has greatly increased the number of women diagnosed with ductal carcinoma in situ (dcis) of the breast. new classifications of dcis recently have been proposed. in this study, these classifications were applied to dcis associated with invasive tumors and correlated with p
## Abstract The interplay between cancer cells and the normal surrounding tissue is believed to influence the biological behavior of the tumor. However, the presence of multiple cell types within the prelevated tumor specimen may attenuate changes that occur specifically in the malignant cells with