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The expression of inducible nitric oxide synthase in human retinal pigment epithelial cells under stimulation of proinflammatory cytokine tumor necrosis factor-α

✍ Scribed by I.-Mo Fang; Chang-Hao Yang; Chung-May Yang; Muh-Shy Chen

Book ID: 116920627
Publisher: Medknow Publications
Year: 2012
Tongue: English
Weight: 390 KB
Volume: 2
Category: Article
ISSN: 2211-5056
DOI: 10.1016/j.tjo.2011.11.001

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## Abstract Nitric oxide (NO) from astrocytes is one of the signalers used by the brain's extensive glial‐neuronal‐vascular network, but its excessive production by pro‐inflammatory cytokine‐stimulated glial cells can be cytodestructive. Here, we show how three pro‐inflammatory cytokines (IL‐1β, TN