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The expression of hepatitis B spliced protein (HBSP) encoded by a spliced hepatitis B virus RNA is associated with viral replication and liver fibrosis

✍ Scribed by Patrick Soussan; Rosella Tuveri; Bertrand Nalpas; Florianne Garreau; Flora Zavala; Annie Masson; Stanislas Pol; Christian Brechot; Dina Kremsdorf

Book ID
118564889
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
139 KB
Volume
38
Category
Article
ISSN
0168-8278

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## Abstract Hepatitis B spliced protein (HBSP) encoded by a 2.2 kb singly spliced hepatitis B virus (HBV) pre‐genomic RNA (spliced between positions 2447 and 489 nt) is involved in the pathogenesis of HBV infection, whereas the exact mechanism is far from being fully elucidated. In this study, a ye