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The expression of CD40-CD40L and activities of matrix metalloproteinases in atherosclerotic rats

โœ Scribed by Min Wu; Yu-Guang Li


Publisher
Springer
Year
2006
Tongue
English
Weight
181 KB
Volume
282
Category
Article
ISSN
0300-8177

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Stimulation of human Bcells via CD40 is known to induce their homotypic aggregation. We show here that anti-mouse CD40 monoclonal antibodies (mAb) also induce B cells to form large, spherical, extremely stable clusters. This clustering is markedly enhanced by co-stimulation with either interleukin-4