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The Expression and Pharmacological Characterization of Nicotinic Acetylcholine Receptor Subunits in HBE16 Airway Epithelial Cells

✍ Scribed by Qi Li; Xiangdong Zhou; Victor P. Kolosov; Juliy M. Perelman


Book ID
113093027
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
629 KB
Volume
62
Category
Article
ISSN
1085-9195

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## Abstract Mammalian secreted lymphocyte antigen‐6/urokinase‐type plasminogen activator receptor‐related peptide‐1 (SLURP‐1) is a positive allosteric ligand for Ξ±7 nicotinic acetylcholine (ACh) receptors (Ξ±7 nAChRs) that potentiates responses to ACh and elicits proapoptotic activity in human kerat