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The expression and functional characterization of sigma (σ) 1 receptors in breast cancer cell lines

✍ Scribed by Ebru Aydar; Pinar Onganer; Rebecca Perrett; Mustafa B. Djamgoz; Christopher P. Palmer

Book ID
116334047
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
568 KB
Volume
242
Category
Article
ISSN
0304-3835

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The EMS1 gene encodes an 80185 kDa C-src substrate and localises with the CCNDl gene to chromosome I lq13. This locus is amplified in approximately 13% of human breast cancers. E M S I gene amplification and expression were charactensed in a panel of human breast cancer cell lines to determine at wh