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The Expressed Heavy Chain V Gene Repertoire of Circulating B Cells in Normal Adults

✍ Scribed by B. DAVID STOLLAR


Book ID
119872576
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
581 KB
Volume
764
Category
Article
ISSN
0890-6564

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## Abstract In early steps of B cell differentiation, ΞΌ chains are transiently expressed in association with a surrogate light chain (Ξ¨L) composed of the λ‐like and VpreB monomorphic polypeptides, thus forming a putative preB receptor. Using a monoclonal anti‐VpreB antibody, preB cells were isolate