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The experimental study of hypoxia-inducible factor-1α and its target genes in spinal cord injury

✍ Scribed by Xiaowei, H; Ninghui, Z; Wei, X; Yiping, T; Cole, Jonathan


Book ID
110074848
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
430 KB
Volume
44
Category
Article
ISSN
1362-4393

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## Abstract We evaluated a role of hypoxia‐inducible factor‐1α (HIF‐1α) and its downstream genes in acute hyperglycemia‐induced hemorrhagic transformation in a rat model of focal cerebral ischemia. Male Sprague‐Dawley rats weighing 280–300 g (n = 105) were divided into sham, 90 min middle cerebral