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The existence of a benzo(a)pyrene-3,6-quinone reductase in rat liver microsomal fractions

✍ Scribed by Jorge Capdevila; Ronald W. Estabrook; Russell A. Prough

Book ID: 118312898
Publisher: Elsevier Science
Year: 1978
Tongue: English
Weight: 448 KB
Volume: 83
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(78)91361-x

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## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex