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The Evolving Systemic and Local Biomarker Milieu at Different Stages of Disease Progression in Rat Adjuvant-Induced Arthritis

✍ Scribed by Marina Stolina; Brad Bolon; Scot Middleton; Denise Dwyer; Heather Brown; Diane Duryea; Li Zhu; Alison Rohner; James Pretorius; Paul Kostenuik; Ulrich Feige; Debra Zack

Publisher: Springer
Year: 2008
Tongue: English
Weight: 526 KB
Volume: 29
Category: Article
ISSN: 0271-9142
DOI: 10.1007/s10875-008-9238-8

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## Abstract We investigated the in vivo effects of the nucleoside transporter inhibitor nitrobenzylmercaptopurine (NBMPR) on rat adjuvant‐induced arthritis. This agent inhibits uptake of adenosine into cells, presumably leading to increased levels of extracellular adenosine. Arthritis was induced i