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The evolutionary origin of the vasopressin/V2-type receptor/aquaporin axis and the urine-concentrating mechanism

✍ Scribed by Juul, Kristian Vinter


Book ID
111879504
Publisher
Springer
Year
2012
Tongue
English
Weight
486 KB
Volume
42
Category
Article
ISSN
0969-711X

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## Abstract The vasopressin V2 receptor (V2R) belongs to the Class A G protein–coupled receptors (GPCRs). V2R is expressed in the renal collecting duct (CD), where it mediates the antidiuretic action of the neurohypophyseal hormone arginine vasopressin (CYFQNCPRG‐NH~2~, AVP). Desmopressin ([1‐deami