The evolution of mammalian transcription factor binding
β Scribed by P. Flicek; D. Schmidt; M. Wilson; B. Ballester; P.C. Schwalie; G. Brown; A. Marshall; C. Kutter; S. Watt; D. Odom
- Publisher
- Elsevier
- Year
- 2010
- Tongue
- English
- Weight
- 46 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1871-6784
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KLF3 is a member of the Kru Β¨ppel-like factor (KLF) family of transcription factors. These proteins are classified by the presence of three C-terminal C2H2 zinc fingers that allow sequence-specific binding to CACCC boxes and GC-rich motifs found in the promoters, enhancers, and other control regions
## Abstract LSF is a mammalian transcription factor that is rapidly and quantitatively phosphorylated upon growth induction of resting, peripheral human T cells, as assayed by a reduction in its electrophoretic mobility. The DNAβbinding activity of LSF in primary T cells is greatly increased after