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The evaluation of formulation and processing conditions of a melt granulation process

✍ Scribed by McTaggart, Celia M.; Ganley, John A.; Sickmueller, Alfred; Walker, Stephen E.

Book ID
120711217
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
878 KB
Volume
19
Category
Article
ISSN
0378-5173

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Co-melt granulation of lactose and PEG was investigated in a fluidised bed granulator. The effect of process parameters such as binder content and binder viscosity were correlated to granulation time and particle size distribution. The experimental data indicated that after initial nucleation the gr