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The evaluation of adenoviral p53-mediated bystander effect in gene therapy of cancer

✍ Scribed by Rizk, Nabil P; Chang, Michael Y; El Kouri, Claude; Seth, Prem; Kaiser, Larry R; Albelda, Steven M; Amin, Kunjlata M


Book ID
110017626
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
421 KB
Volume
6
Category
Article
ISSN
0929-1903

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Background: Gene therapy of human tumors with adenovirus vectors presents a clinical research challenge and a potential opportunity in cancer therapy. One of the research challenges is that endpoints like tumor reduction, time to recurrence, and survival do not provide information about whether a po