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The eukaryotic nucleotide excision repair pathway

✍ Scribed by Renata M.A. Costa; Vanessa Chiganças; Rodrigo da Silva Galhardo; Helotonio Carvalho; Carlos F.M. Menck

Book ID: 116308259
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 810 KB
Volume: 85
Category: Article
ISSN: 0300-9084
DOI: 10.1016/j.biochi.2003.10.017

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## Abstract Nucleotide excision repair (NER) is the primary DNA repair pathway that removes helix‐distorting DNA strand damage induced by ultraviolet light irradiation or chemical carcinogens to ensure genome integrity. While the core NER proteins that carry out damage recognition, excision, and re