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The ETS Protein MEF Plays a Critical Role in Perforin Gene Expression and the Development of Natural Killer and NK-T Cells

✍ Scribed by H.Daniel Lacorazza; Yasushi Miyazaki; Antonio Di Cristofano; Anthony Deblasio; Cyrus Hedvat; Jin Zhang; Carlos Cordon-Cardo; Shifeng Mao; Pier Paolo Pandolfi; Stephen D. Nimer


Book ID
117723281
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
857 KB
Volume
17
Category
Article
ISSN
1074-7613

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## Abstract ## Objective CD1d‐reactive invariant natural killer T (iNKT) cells secrete multiple cytokines upon T cell receptor (TCR) engagement and modulate many immune‐mediated conditions. The purpose of this study was to examine the role of these cells in the development of autoimmune disease in