The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma
โ Scribed by T. Rothhammer; J.C. Hahne; A. Florin; I. Poser; F. Soncin; N. Wernert; A.-K. Bosserhoff
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 546 KB
- Volume
- 61
- Category
- Article
- ISSN
- 1420-682X
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## Abstract Transcription factor Etsโ1 is induced in endothelial cells (ECs) by angiogenic factors, and promotes angiogenesis by inducing angiogenesisโrelated genes such as MMPs and integrin ฮฒ3. Here, we examined the effect of Etsโ1 on apoptosis in ECs. Overexpression of Etsโ1 in human umbilical ve