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The estrous cycle affects cocaine self-administration on a progressive ratio schedule in rats

โœ Scribed by D. C. S. Roberts; S. A. L. Bennett; G. J. Vickers

Publisher
Springer
Year
1989
Tongue
English
Weight
513 KB
Volume
98
Category
Article
ISSN
0033-3158

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Self-administration of cocaine on a prog
Self-administration of cocaine on a progressive ratio schedule in rats: dose-response relationship and effect of haloperidol pretreatment
โœ David C. S. Roberts; Elliot A. Loh; Gary Vickers ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 414 KB

Intravenous cocaine self-administration behavior in rats was investigated using a progressive ratio (PR) schedule of reinforcement. The first response on the lever each day produced a drug infusion, whereupon the requirements of the schedule escalated with each reinforcement until the behavior extin