## Abstract Exposure to exogenous (oral contraceptives, postmenopausal hormone therapy) and endogenous (number of ovulatory cycles, adiposity) steroid hormones is associated with breast cancer risk. Breast cancer risk associated with these exposures could hypothetically be modified by genes in the
✦ LIBER ✦
The Estrogen Receptor α Gene and Breast Cancer Risk (The Netherlands)
✍ Scribed by N. Charlotte Onland-Moret; Carla H. Gils; Mark Roest; Diederick E. Grobbee; Petra H. M. Peeters
- Publisher
- Springer Netherlands
- Year
- 2005
- Tongue
- English
- Weight
- 210 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0957-5243
No coin nor oath required. For personal study only.
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## Abstract Estrogens exert their effect on the breast through the estrogen receptor. We prospectively investigated breast cancer risk associated with 2 polymorphic sites in the estrogen receptor alpha gene (__ESR1__). A total of 4,248 Caucasian women from the Study of Osteoporotic Fractures were g