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The Epoxidation of 1-Acetoxycyclohexene and the Rearrangement of 1-Acetoxy-1,2-epoxycyclohexane 1

โœ Scribed by Shine, H. J.; Hunt, G. E.


Book ID
127054091
Publisher
American Chemical Society
Year
1958
Tongue
English
Weight
272 KB
Volume
80
Category
Article
ISSN
0002-7863

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Corynebacterium C12 epoxide hydrolase transforms (ยฑ)-l-methyl-l,2-epoxycyclohexane 1 to the (I-S, 2-S)-l-methylcyclohexane-l,2-diol 2 leaving the (1-S, 2-R)epoxide 3 unchanged. The diol 2 is converted to the the (l-R, 2-S )-epoxide 4 by sulfonationring closure. A one pot combination of Corynebacteri