The Epigenetics of Germ-line Immortality: Lessons from an Elegant Model System

Establishment and characterization of im

Establishment and characterization of immortalized neuronal cell lines derived from the spinal cord of normal and trisomy 16 fetal mice, an animal model of Down syndrome

✍ Ana María Cárdenas; David D. Allen; Christian Arriagada; Alexis Olivares; Lori B 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 486 KB

## Abstract We report the establishment of continuously growing cell lines from spinal cords of normal and trisomy 16 fetal mice. We show that both cell lines, named M4b (derived from a normal animal) and MTh (trisomic) possess neurological markers by immunohistochemistry (neuron specific enolase,