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The epidermal growth factor stimulates sphingosine kinase-1 expression and activity in the human mammary carcinoma cell line MCF7

✍ Scribed by Frauke Döll; Josef Pfeilschifter; Andrea Huwiler

Book ID
116273005
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
459 KB
Volume
1738
Category
Article
ISSN
1388-1981

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In the human glioblastoma cell line, T-MG1, plasminogen activator activity (PA-activity) was demonstrated by using the chromogenic substrate S-2251. Using monoclonal antibodies against human urokinase type PA (u-PA) and human tissue type PA (t-PA), only u-PA activity was found in T-MG1 cell extracts