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The epidermal growth factor receptor in malignant gliomas: pathogenesis and therapeutic implications

โœ Scribed by Nakamura, Jean L


Book ID
118053442
Publisher
Informa plc
Year
2007
Tongue
English
Weight
178 KB
Volume
11
Category
Article
ISSN
1472-8222

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Epidermal growth factor (EGF) and transforming growth factor-alpha (TGFo0 are two closely related peptides that interact with cell-surface epidermal growth factor receptors (EGFR) to induce receptor tyrosine phosphorylation and activation of intracellular signal-transduction pathways. EGF appears to