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The epidemiology of HER-2 positive tumours

✍ Scribed by D. Kulkarni; Beechey-Newman; A. Kothari; H. Hamed; C. D'Arrigo; K. Ryder; I. Fentiman

Book ID: 118624382
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 141 KB
Volume: 4
Category: Article
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(06)80102-3

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## Abstract Chromosomal instability (CIN) is a common cause of tumour heterogeneity and poor prognosis in solid tumours and describes cell–cell variation in chromosome structure or number across a tumour population. In this article we consider evidence suggesting that CIN may be targeted and may in