✦ LIBER ✦

[The Enzymes] Volume 27 || Rag GTPases in TORC1 Activation and Nutrient Signaling

✍ Scribed by Li, Li

Book ID: 120332257
Publisher: Elsevier
Year: 2010
Tongue: English
Weight: 131 KB
Edition: 1
Category: Article
ISBN: 0123815398
DOI: 10.1016/S1874-6047(10)27005-1

No coin nor oath required. For personal study only.

✦ Synopsis

Cell growth is highly regulated and is controlled by the TOR signaling network. Dysfunction of signaling pathways controlling cell growth results in cells of altered sizes and in turn causes developmental errors and a wide range of pathological conditions. An understanding of the TOR signaling network may lead to novel drugs for the treatment of, for example, cancer, diabetes, inflammation, muscle atrophy, learning disabilities, depression, obesity and aging.

There has been an explosion of knowledge in this area in recent years and this volume provides an in-depth review of our current knowledge of TOR complexes by the leaders in the field.

* Contributions from leading authorities
* Informs and updates on all the latest developments in the field

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