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The enhancement of the effect of aflatoxin B1 by metabolic activation with rat-liver microsomes on human lymphocytes assayed with the micronucleus test

โœ Scribed by O. Iskandar; Vijayalaxmi

Book ID
113254071
Publisher
Elsevier Science
Year
1981
Weight
192 KB
Volume
91
Category
Article
ISSN
0165-7992

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Fisher-344 male rats were fed 1.6 ppm of aflatoxin B 1 (AFB 1 ) continuously and intermittently for several weeks. At various time periods, DNA was isolated from the testes and livers and analyzed for AFB 1 -DNA adducts. The ability of the testis to detoxify AFB 1 was also investigated by the glutat