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The enhancement of sensitivity of HL-60 cells to arsenic trioxide by Bcl-2 siRNA

✍ Scribed by Haiyan Hu; Yuan Zhang; Dongmei He


Publisher
Springer
Year
2007
Tongue
English
Weight
264 KB
Volume
6
Category
Article
ISSN
1610-1979

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## Abstract The P‐glycoprotein (p170, P‐gp) encoded by human __MDR1__ gene functions as a pump to extrude anticancer drugs from cancer cells. Over‐expression of p170 is closely related to primary and induced drug resistance phenotype of tumor cells. Recent studies have demonstrated that expression