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The enhancement of riboflavin-mediated photo-oxidation of doxorubicin by histidine and urocanic acid

โœ Scribed by Avner Ramu; Michelle M. Mehta; Thaddeus Leaseburg; Aleksandar Aleksic


Publisher
Springer
Year
2001
Tongue
English
Weight
159 KB
Volume
47
Category
Article
ISSN
0344-5704

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UV-B radiation suppresses cell-mediated immunity. Histidine forms trans-urocanic acid (truns-UCA) enzymatically in the stratum comeum. Photoisomerization of trans-UCA to cis-urocanic acid (cis-UCA) has been proposed for the initiation of an immunosuppressive process. Many microorganisms described in