The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain
✍ Scribed by Richard J. Clark; Jonas Jensen; Simon T. Nevin; Brid P. Callaghan; David J. Adams; David J. Craik
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 514 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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## Abstract Neuronal nicotinic acetylcholine receptor (nAChR) agonists have been demonstrated to exhibit antinociceptive, antihyperalgesic, and antiallodynic effects across a range of preclinical models of pain. Yet, to date, no drugs have been successfully developed and approved for the treatment