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The Energy Landscape of Unsolvated Peptides: The Role of Context in the Stability of Alanine/Glycine Helices

โœ Scribed by Hartings, Matthew R.; Kinnear, Brian S.; Jarrold, Martin F.


Book ID
126057908
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
229 KB
Volume
125
Category
Article
ISSN
0002-7863

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โœ Jeffery G. Saven; Peter G. Wolynes ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 446 KB

Using simple statistical mechanical models, we present a theory based on a free energy function that combines classical models of the helix-coil transition in polymers with approximate treatments of the effects of excluded volume, confinement, and helical packing. The theory includes "local signals"