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The energy charge in wild-type and respiration-deficient chinese hamster cell mutants

✍ Scribed by K. Soderberg; E. Nissinen; B. Bakay; I. E. Scheffler

Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
324 KB
Volume
103
Category
Article
ISSN
0021-9541

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✦ Synopsis

Abstract

High pressure liquid chromatography was used to determine the base, nucleoside, and nucleotide levels in wild type and a series of respiration‐deficient Chinese hamster cell mutants. From this analysis the size of the total adenylate pool and the energy charge could be calculated for each cell line. We find a constant energy charge, as expected, but the adenylate pool seems to be considerably lower in the respiration‐deficient mutants.

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