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The energetics of small internal loops in RNA

✍ Scribed by Susan J. Schroeder; Mark E. Burkard; Douglas H. Turner

Publisher
Wiley (John Wiley & Sons)
Year
1999
Tongue
English
Weight
204 KB
Volume
52
Category
Article
ISSN
0006-3525

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## Dedicated to Prof. Dr. Frank Seela on the occasion of his 60th birthday The hydrolysis of phosphodiester bonds of chimeric 2'-O-methyloligoribonucleotides was studied in buffer solutions. Pseudo-first-order rate constants for cleavage of phosphodiester bonds within hairpin loops were calculated