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The Endosomal Trafficking of Apolipoprotein E3 and E4 in Cultured Human Brain Neurons and Astrocytes

✍ Scribed by Robert M. DeKroon; Patricia J. Armati


Book ID
115641588
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
760 KB
Volume
8
Category
Article
ISSN
0969-9961

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## Abstract Human immunodeficiency virus type 1 (HIV‐1)‐associated dementia is observed in 20–30% of patients with acquired immunodeficiency syndrome (AIDS). The Ο΅4 allele of the apolipoprotein E (APOE) gene currently is thought to play a role as a risk factor for the development of HIV dementia. T