The endogenous lipid anandamide is a ful
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D Smart; M J Gunthorpe; J C Jerman; S Nasir; J Gray; A I Muir; J K Chambers; A D
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Article
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2000
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Nature Publishing Group
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English
β 136 KB
The endogenous cannabinoid anandamide was identified as an agonist for the recombinant human VR1 (hVR1) by screening a large array of bioactive substances using a FLIPRβbased calcium assay. Further electrophysiological studies showed that anandamide (10 or 100βΞΌM) and capsaicin (1βΞΌM) produced simil