Theiler's murine encephalomyelitis virus (TMEV) is known to interact with cells of the central nervous system (CNS). Here we report that, interestingly, it is a potent inductor of interleukin-6 (IL-6) in the CNS of infected animals and in pure cultures of astrocytes. Maximal IL-6 gene transcription
β¦ LIBER β¦
The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway
β Scribed by Francisco Molina-Holgado; Eduardo Molina-Holgado; Carmen Guaza
- Book ID
- 117109501
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 286 KB
- Volume
- 433
- Category
- Article
- ISSN
- 0014-5793
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Theiler's murine encephalomyelitis virus (TMEV) infection in the central nervous system (CNS) induces a demyelinating disease similar to human multiple sclerosis. TMEV infection results in activation of various chemokine and cytokine genes that are important in the initiation of an inflammatory resp